Orlistat is used to treat obesity and help in weight loss. Orlistat is to be used along with a low-calorie diet and regular physical exercise. Obesity is a common condition associated with excessive body fat, which in turn increases the risk of other health problems such as diabetes, high blood pressure, certain cancers, and heart disease. Intake of more calories than you burn by exercise or daily activities results in obesity.
Orlistat contains Orlistat, which works in the small intestine and stomach and prevents the action of enzymes that break down fat, which is absorbed by the body. Orlistat decreases the absorption of fat from the food you eat. Thus, fat passes through the gut and is excreted in the faeces, which makes the body unable to use fat as a source of energy or convert it into fat tissue. Thereby, Orlistat helps in weight loss.
Take Orlistat as prescribed by your doctor. You are advised to take Orlistat for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience soft stools, sudden bowel motions, flatulence (gas) with or without oily spotting, oily or fatty stools, stomach pain, stool incontinence (involuntary leakage of stools), and runny or liquid stools. Most of these side effects of Orlistat do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
If you are allergic to Orlistat or any other medicines, please tell your doctor. Avoid taking Orlistat if you are pregnant or planning for pregnancy, as it may cause fetal harm. It is not known whether Orlistat is excreted in human milk. Therefore, please consult a doctor if you are a breastfeeding woman. Orlistat is not recommended for children below 18 years of age, as the safety and effectiveness were not established. You are advised to take a multivitamin containing fat-soluble vitamins such as A, D, E, and K at bedtime as Orlistat may reduce the absorption of certain vitamins in the body.
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The aim of this trial is to evaluate the efficacy and safety of Orlistat (Xenical®) in the treatment of obesity in obese women. The trial was conducted in 3 clinical and 3 preclinical studies in women with obesity (body mass index [BMI] ≥ 30 kg/m2 or ≥ 27 kg/m2) who were eligible to participate in this trial. The primary objective was to determine the efficacy and safety of the treatment.
Study design
This study was a randomized, double-blind, placebo-controlled, parallel group, double-masked study that was conducted in 3 clinical and 3 preclinical studies. The study was conducted between July 2011 and June 2013 at 3 academic medical centers. All subjects were between 21 and 42 years old.
For the primary outcome, the primary efficacy and safety data were collected at each stage of the study. The primary efficacy end point was the change from baseline to the end of the treatment course. The primary safety end point was the proportion of patients achieving at least one weight-related weight-related weight loss in the study.
The study was terminated in October 2014.
The study was conducted in 3 clinical and 3 preclinical studies in women with obesity (body mass index [BMI] ≥ 30 kg/m2 or ≥ 27 kg/m2) who were eligible to participate in this study.
Study setting
Study participants
Primary outcome
The weight change from baseline to the end of the treatment course.
DescriptionOrlistat (Xenical capsules) is a well-known weight loss medication. Xenical capsules contain orlistat, which works by inhibiting an enzyme called lipase, which helps reduce fat absorption. Xenical capsules are used to reduce the amount of fat absorbed from a diet that is high in fat. These medications are designed for use in people with a body mass index (BMI) of 28 or higher. Weight loss is usually achieved through a combination of diet and exercise. Diet and exercise can help to increase body weight and reduce the amount of fat absorbed from food. Weight loss is also a good idea if the person has been trying to lose weight by eating a healthy diet and exercising regularly. Orlistat is a prescription drug that you must take regularly as it works by blocking the absorption of some of the fat that is absorbed from food. If you are taking Orlistat, it is important to tell your doctor and pharmacist if you are taking any other medications, including any that you are taking, because there may be interactions between Orlistat and other drugs. This will help your doctor know if Orlistat is right for you and will make sure you follow the dosage instructions on the label. If you are taking any of the following medications, tell your doctor if you are taking:
• Allopurinol (Doxazosin) or • Benadryl (Dasubutraz) • Calcium channel blockers like riociguat (Vivactil) • Lidocaine (Lipitor) • Phenylephrine (Adderall) • Xazosin (Xopenex) •You should not take Orlistat if you are not on any of the following medications: • Metformin • Orlistat (Xenical) • Phenylalanine supplementation • Phenobarbital (Paxil) • Pimozide • Tricyclic antidepressants like amitriptyline • Thioridazine • Antibiotics like erythromycin • St John’s Wort (Hypericum perforatum) • Any other medications that you are taking that interact with orlistat. Tell your pharmacist if you are taking any of these medications: • Diclofenac • Isosorbide dinitrate (Isordil) • Isosorbide mononitrate (Monoket) • Nitroglycerin • Nitrostat (Minitran) • Nitrostat SR • Nitrostat XL • St. John’s Wort (Hypericum perforatum) • Any other medications that you are taking that interact with orlistat. Tell your pharmacist if you are taking any of the following medications: • Warfarin (Coumadin) • Isosorbide dinitrate (Isordil) • Isosorbide mononitrate (Monoket) • St John’s Wort (Hypericum perforatum) • Any other medications that you are taking that interact with orlistat. Tell your pharmacist if you are taking any of the following medications: • Amiodarone • Cimetidine • D-lucor • Any other medications that you are taking that interact with orlistat. Tell your pharmacist if you are taking any of the following medications: • Any other medications that you are taking that interact with orlistat.
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Alli is a top weight-loss brand in Turkey,...View MoreAlli is a top weight-loss brand in Turkey, offering a range of effective products. With trusted reviews and a commitment to quality, Alli helps individuals achieve their weight-loss goals safely and efficiently.View LessRead More
Alli is a brand of medication that is used for weight loss. It contains the active ingredient Orlistat, which blocks the absorption of fat in the body. Alli is sold over-the-counter and is meant to be used in combination with a low-fat, reduced-calorie diet and exercise program.
- Alli was launched in 2007 by GlaxoSmithKline.
- It was the first FDA-approved over-the-counter weight loss medication.
- In 2014, ownership of the brand was transferred to the British company Reckitt Benckiser.
- Alli is currently available in the United States, the United Kingdom, and Australia.
Xenical is a prescription weight loss medication that also contains Orlistat as its active ingredient. It is marketed by Roche Pharmaceuticals and is available in many countries around the world.
PhenQ is a weight loss supplement that contains a blend of natural ingredients. It is marketed by a company called Wolfson Berg Limited and is available for purchase online.
Hydroxycut is a brand of weight loss supplements that are marketed by Iovate Health Sciences International. The brand offers a variety of products that contain different active ingredients, such as caffeine and green coffee extract.
Alli Capsules are the brand's flagship product. Each capsule contains 60mg of Orlistat and is meant to be taken with meals that contain fat.
Alli is used for weight loss. It works by blocking the absorption of fat in the body.
Alli is meant to be taken with meals that contain fat. You should also follow a low-fat, reduced-calorie diet and exercise program while taking this medication.
Alli is generally considered safe when used as directed. However, it can cause some side effects, such as diarrhea and abdominal pain.
Studies have shown that people who take Alli in combination with a diet and exercise program can lose up to 5% of their body weight within six months.
No, Alli is not recommended for use during pregnancy or breastfeeding.
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aintment_adult_18_gsk_md_md_compare_compare_lg_contraindication_percent_weight_of_girl_alli_lg_compared_to_other weight loss supplementaintment_adult_18_gsk_md_compare_compare_weight_of_girl_alli_lg_gsk_alli_gsk_md_product_id_id_id_12371408785918gsk_purchase_alliHealthy weight loss
Top tips for healthy weight loss:
To help you find out if you have a healthy body weight, measure your and waist circumference To lose weight, the energy you take in from food must be less than the energy you use – eat less, move more!
Set yourself realistic goals to achieve a healthy weight. Even small amounts of weight loss can have significant health benefits and can help to set you on a path to a healthier future. Guidelines recommend that you should try to lose weight gradually, about 1-2 lbs (approximately 0.5-1.0 kg) a week
Weight loss can reduce your risk of: heart disease, stroke, type 2 diabetes and some cancers.
It can also reduce the risk of:
High blood pressure Angina (heart condition causing chest pain) High blood cholesterol levels Lower back and joint pain Fertility problems BMI and waist circumference
For most adults:
A BMI between 18.5 and 25 is defined as healthy. A BMI of over 25 is defined as overweight. A BMI of over 30 is defined as obese.
Waist-circumferences for which there is an increased risk and high risk of obesity-related health problems:
Increased risk High risk Men ≥94 cm (37 in) ≥102 cm (40 in) Women ≥80 cm (31.5 in) ≥88 cm (34.5 in)
Sensible weight loss should be seen as an overall lifestyle change which involves eating a healthy balanced diet and doing plenty of physical activity.
Guidelines recommend that you should try to lose weight gradually, about 1-2 lbs (approximately 0.5-1.0 kg) a week. This way, the weight is more likely to stay off. This rate of weight loss is based on using up 600 kcal per day more than you take in. On average, this means consuming no more than 1,400 kcal a day if you are a women, and no more than 1,900 kcal a day if you are a man. The amount of weight you lose will depend on how much weight you need to lose and how active you are.
Further information can be found on the manufacturers
Side Effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Orlistat.
The majority of unwanted effects related to the use of Orlistat result from its local action in your digestive system. These symptoms are generally mild, occur at the beginning of treatment and are particularly experienced after meals containing high levels of fat. Normally, these symptoms disappear if you continue treatment and keep to your recommended diet.
Very common (may affect more than 1 in 10 people):
headache abdominal pain/discomfort urgent or increased need to open the bowels flatulence (wind) with or without discharge oily discharge, oily or fatty stools liquid stools low blood sugar levels (experienced by some people with type 2 diabetes) upper respiratory infections flu (influenza)
You may experience the following side effects: nausea, vomiting, headache, flushing, dizziness and diarrhoea high cholesterol and triglycerides eye problems high blood pressure high blood sugar levels (experienced by some people with type 2 diabetes) cholesterol and fats increased high energy goal meal times or Celsius less than 22.8 mean hours
Occasional (fever, shortness of breath, symptoms of heart disease):
unexplained swelling or pain around the painful opening of the bowels throwing patients into the stools frusemide distpictured new oily discharge, oily or fatty stools persistent oily stools oily stools or frequent stools pain This is not every day, and it is likely that many people will experience more severe side effects. Some people have experienced severe allergic reactions (including rash, itching, swelling, difficulty breathing and severe dizziness) in response to this medication.
No experience had built into the manufacturer's information on medical advice about side effects. If you are taking any of the following medicines, it is important that they are discussed with your doctor:
Orlistat is an oral prescription medication which contains the active ingredient Orlistat, which is an orlistat type of drug known as a biguanide.
Stade de France Pharmacy